Vancomycin Continuous Infusion Rate

Vancomycin continuous infusion arithmetic: loading dose and daily dose on actual body weight, the pump rate in mg/h and mL/h, each set against the 2020 consensus guideline ranges, and the bag concentration against the FDA label.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Actual body weight
70 kg
Loading dose
20 mg/kg
Daily dose
35 mg/kg/day
Bag concentration
5 mg/mL

Result: Load 1,400 mg, then 102.1 mg/h (2,450 mg/day, 20.42 mL/h).

The tool opens with these values already filled in. Replace them with your own.

What you enter

  • Actual body weight
  • Loading dose (guideline 15 to 20)
  • Daily dose (guideline 30 to 40, up to 60)
  • Bag concentration
  • Steady-state level (optional)
  • Current rate (with a level)
  • Target level (guideline 20 to 25)
How this is calculated

Citation

Rybak MJ, et al. Am J Health-Syst Pharm 2020;77:835-864 (ASHP/IDSA/PIDS/SIDP vancomycin guideline), recommendation 7: continuous infusion loading 15 to 20 mg/kg, 30 to 40 (up to 60) mg/kg/day, steady state 20 to 25 mg/L, AUC24 = level × 24. FDA label on DailyMed: concentration. Read the sources: Rybak 2020 guideline ↗, Vancomycin label ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.