Leibovich Score (clear-cell RCC progression)
Leibovich progression score (Leibovich 2003, clear-cell RCC after radical nephrectomy) — an additive 0-11 recurrence-risk model over five pathology factors.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Primary tumor stage
- pT3–pT4 (+4)
- Regional lymph nodes
- pNx / pN0 (0)
- Tumor size
- < 10 cm (0)
- Nuclear (Fuhrman) grade
- Grade 4 (+3)
- Coagulative tumor necrosis present
- Yes
Result: Leibovich progression score 8/11
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0–2
- Low risk — ~97% 5-year metastasis-free survival.
- 3–5
- Intermediate risk — ~74% 5-year metastasis-free survival.
- ≥ 6
- High risk — ~31% 5-year metastasis-free survival; the group selected for adjuvant trials.
What you enter
- Primary tumor stage (pT1a / pT1b / pT2 / pT3-pT4)
- Regional lymph nodes (pNx/pN0 or pN1/pN2)
- Tumor size (< 10 cm or >= 10 cm)
- Nuclear (Fuhrman) grade
- Coagulative tumor necrosis present
How this is calculated
- Factors
- pT stage (pT1a 0, pT1b +2, pT2 +3, pT3-pT4 +4); nodes pN1/pN2 +2; tumor size >= 10 cm +1; Fuhrman grade 3 +1 / grade 4 +3; coagulative necrosis +1.
Leibovich BC, Blute ML, Cheville JC, et al. Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma: a stratification tool for prospective clinical trials. Cancer. 2003;97(7):1663-1671. Five factors, total 0-11; low 0-2, intermediate 3-5, high >= 6. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.