IMDC (Heng) Metastatic RCC Risk
International Metastatic RCC Database Consortium (IMDC / Heng) risk group for metastatic renal-cell carcinoma from six clinical/laboratory factors.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Karnofsky < 80%
- Yes
- Anemia
- Yes
- Hypercalcemia
- Yes
Result: IMDC: 3 factors — poor risk (median OS 7.8 mo).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Groups
- Favorable 0, intermediate 1–2, poor ≥ 3.
What you enter
- Karnofsky < 80%
- Diagnosis to systemic therapy < 1 year
- Anemia (Hb < LLN)
- Hypercalcemia
- Neutrophilia (> ULN)
- Thrombocytosis (> ULN)
How this is calculated
- Factors
- Karnofsky < 80%, dx-to-therapy < 1 y, anemia, hypercalcemia, neutrophilia, thrombocytosis (1 point each).
Heng DYC, Xie W, Regan MM, et al. Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor–targeted agents. J Clin Oncol. 2009;27(34):5794-5799. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.