Durie-Salmon Staging (Multiple Myeloma)
Durie-Salmon staging (Durie 1975): hemoglobin, serum calcium, lytic bone lesions, and M-protein burden give stage I–III, subclassified A/B by renal function (creatinine).
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Hemoglobin
- 7 g/dL
- Serum calcium
- 10 mg/dL
- Number of lytic bone lesions
- 4
- M-protein burden
- High (IgG > 7, IgA > 5 g/dL; urine BJ > 12 g/24h)
- Serum creatinine
- 1.0 mg/dL
Result: Durie-Salmon stage IIIA.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Stage I
- Hb > 10, normal calcium, 0-1 bone lesion, low M-protein.
- Stage III
- Any of Hb < 8.5, calcium > 12, >= 3 lytic lesions, high M-protein.
- Subclass
- A = creatinine < 2.0, B = >= 2.0 mg/dL. A staging classification, not a treatment order.
What you enter
- Hemoglobin
- Serum calcium
- Number of lytic bone lesions
- M-protein burden (low/intermediate/high)
- Serum creatinine
How this is calculated
Durie BGM, Salmon SE. A clinical staging system for multiple myeloma: correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer. 1975;36(3):842-854. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.