IMPEDE VTE Score (Myeloma)

IMPEDE-VTE score for venous-thromboembolism risk in multiple myeloma on therapy; the weighted sum maps to a low/intermediate/high 6-month VTE band.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Immunomodulatory agent
Yes
Dexamethasone dose
High-dose (≥ 160 mg/month) — +4
Prior VTE
Yes

Result: IMPEDE VTE 13 — high VTE risk.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Bands
≤ 3 low, 4–7 intermediate, ≥ 8 high VTE risk.

What you enter

  • Immunomodulatory agent (+4)
  • BMI ≥ 25 kg/m² (+1)
  • Pelvic / hip / femur fracture (+4)
  • Erythropoietin-stimulating agent (+1)
  • Dexamethasone dose
  • Doxorubicin (+3)
  • Asian ethnicity (−3)
  • Prior VTE (+5)
The other 2 fields
  • Tunneled line / central venous catheter (+2)
  • Existing thromboprophylaxis
How this is calculated
Weights
IMiD +4, BMI ≥ 25 +1, fracture +4, ESA +1, dexamethasone +4/+2, doxorubicin +3, Asian −3, prior VTE +5, CVC +2, prophylaxis −4/−3.

Sanfilippo KM, Luo S, Wang TF, et al. Predicting venous thromboembolism in multiple myeloma: development and validation of the IMPEDE VTE score. Am J Hematol. 2019;94(11):1176-1184. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.