Multiple myeloma ISS stage
International Staging System for multiple myeloma (Greipp 2005): β2-microglobulin and albumin map to stage I–III.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- β2-microglobulin
- 3.2
- Albumin
- 4
Result: Multiple myeloma ISS stage I (beta2-microglobulin 3.2 mg/L, albumin 4 g/dL; beta2-microglobulin < 3.5 and albumin >= 3.5) -- median overall survival ~62 months in the 2005 derivation cohort.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- I
- β2-microglobulin < 3.5 mg/L AND albumin ≥ 3.5 g/dL; median OS ~62 months.
- II
- Neither the stage-I nor the stage-III definition; median OS ~44 months.
- III
- β2-microglobulin ≥ 5.5 mg/L; median OS ~29 months.
What you enter
- β2-microglobulin (mg/L)
- Albumin (g/dL)
How this is calculated
Greipp PR, San Miguel J, Durie BGM, et al. International staging system for multiple myeloma. J Clin Oncol. 2005;23(15):3412-3420. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.