Gage pharmacogenomic warfarin dose
Gage pharmacogenomic warfarin dose: a published exponential model predicting the therapeutic daily dose from body-surface area, age, target INR, smoking, amiodarone, race, DVT/PE indication, and the CYP2C9 / VKORC1 genotypes.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 60 years
- Height
- 175 cm
- Weight
- 70 kg
- Target INR
- 2.5
- VKORC1 (-1639 G>A) genotype
- G/G
- CYP2C9 genotype
- *1/*1
- Amiodarone
- No
- Current smoker
- No
- African-American race
- No
- DVT / PE indication
- No
Result: Gage predicted therapeutic dose 6.3 mg/day
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Age
- Height
- Weight
- Target INR
- VKORC1 (-1639 G>A) genotype
- CYP2C9 genotype
- Amiodarone
- Current smoker
- African-American race
- DVT / PE indication
How this is calculated
Citation
Gage BF, Eby C, Johnson JA, et al. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther. 2008;84(3):326-331. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.