Gage pharmacogenomic warfarin dose
Gage pharmacogenomic warfarin dose: a published exponential model predicting the therapeutic daily dose from body-surface area, age, target INR, smoking, amiodarone, race, DVT/PE indication, and the CYP2C9 / VKORC1 genotypes.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 60 years
- Height
- 175 cm
- Weight
- 70 kg
- Target INR
- 2.5
- VKORC1 (-1639 G>A) genotype
- G/G
- CYP2C9 genotype
- *1/*1
- Amiodarone
- No
- Current smoker
- No
- African-American race
- No
- DVT / PE indication
- No
Result: Gage predicted therapeutic dose 6.3 mg/day
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Age
- Height
- Weight
- Target INR
- VKORC1 (-1639 G>A) genotype
- CYP2C9 genotype
- Amiodarone
- Current smoker
- African-American race
- DVT / PE indication
How this is calculated
Gage BF, Eby C, Johnson JA, et al. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther. 2008;84(3):326-331. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.