Pediatric Warfarin Protocol (CHEST 2012)

Pediatric warfarin protocol for a target INR of 2.0 to 3.0 (CHEST 2012 with the 2024 ASH/ISTH guideline).

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Phase
Maintenance
INR
1.7
Loading dose or current dose
5 mg

Result: INR 1.7 in maintenance (1.5-1.9): increase by 10%, 5.5 mg.

The tool opens with these values already filled in. Replace them with your own.

What you enter

  • Phase
  • INR (baseline on day 1)
  • Day 1 start
  • Weight (day 1)
  • Loading dose or current dose
How this is calculated

Citation

Monagle P et al. CHEST 2012;141(2 Suppl):e737S-e801S, Table 6, with the band printed "1.15-1.9" read as 1.5-1.9 per Monagle P et al. ASH/ISTH 2024 pediatric VTE guidelines, Blood Adv 2025;9:2587, Table 9. Read the sources: CHEST 2012, Table 6 ↗, ASH/ISTH 2024, Table 9 ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.