Naloxone Dosing Calculator

Select adult or pediatric, pick a route (IV, IM, intranasal, or subcutaneous), and enter the pediatric weight if needed.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Population
Adult
Route
Intranasal

Result: Initial: 4 mg intranasal (1 spray each nostril).

The tool opens with these values already filled in. Replace them with your own.

What you enter

  • Population
  • Route (IV / IM / intranasal / SC)
  • Pediatric weight (if pediatric)

What this is

Sophie Well returns the initial dose, the re-dose interval, and the typical maximum or escalation per FDA labeling and CDC opioid-overdose guidance. Reference values are stated in mg; intranasal is given as the standard pre-filled-device dose.

When to use it

Use this when you have to dose naloxone right now and want to verify the math before you push, or when teaching the dose to a community-response training. Bystander naloxone (the 4 mg intranasal device) does not require a calculation; this tool exists for the clinical scenarios where it does.

How this is calculated

Naloxone HCl FDA labeling. CDC opioid overdose guidance. Repeat q2-3 min until adequate respirations.

Source: FDA prehospital drug labeling subset

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.