Gentamicin, Tobramycin, Amikacin: Label Dosing by Creatinine
Conventional (multiple daily dose) gentamicin, tobramycin or amikacin dosing by each FDA label.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Drug
- Gentamicin
- Severity (gentamicin, tobramycin)
- Serious infection
- Actual body weight
- 60 kg
- Dose on actual weight or a lean estimate
- Actual body weight
- Serum creatinine
- 2 mg/dL
Result: Gentamicin on 60 kg: usual 60 mg every 8 hours (3 mg/kg/day). At a creatinine of 2 mg/dL: 60 mg every 16 hours, or 30 mg every 8 hours.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Drug
- Severity (gentamicin, tobramycin): serious or life
- Actual body weight
- Dose on actual weight or a lean estimate
- Lean weight estimate (if dosing on it)
- Serum creatinine
How this is calculated
Citation
FDA labels on DailyMed, Dosage and Administration: gentamicin (interval = serum creatinine × 8; Table 4), tobramycin (× 6; lean weight plus 40% of the excess) and amikacin (× 9; 1.5 g/day ceiling); each label's usual dose ÷ serum creatinine rough guide. Read the sources: Gentamicin label ↗, Tobramycin label ↗, Amikacin label ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.