Extended-interval aminoglycoside (Hartford)
Hartford extended-interval aminoglycoside dosing (Nicolau 1995): gentamicin/tobramycin 7 mg/kg or amikacin 15 mg/kg with a CrCl-derived starting interval.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Drug
- Gentamicin (7 mg/kg)
- Dosing weight
- 70 kg
- Creatinine clearance
- 80 mL/min
Result: Dose 490 mg (7 mg/kg), starting interval q24h; refuses dialysis.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Drug
- Dosing weight
- Creatinine clearance
- On dialysis
How this is calculated
Nicolau DP, et al. Antimicrob Agents Chemother. 1995;39(3):650-655 (Hartford extended-interval aminoglycoside). Gentamicin/tobramycin 7 mg/kg, amikacin 15 mg/kg; starting interval set from CrCl, random level plotted on the printed Hartford nomogram. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.