Cockcroft-Gault Creatinine Clearance
Estimate creatinine clearance using the original Cockcroft-Gault formula (Nephron 1976): CrCl = ((140 - age) * weight in kg) / (72 * serum creatinine in mg/dL), with a 0.85 multiplier for female sex.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 60 years
- Weight
- 80 kg
- Serum creatinine
- 1.0 mg/dL
- Sex
- Male
Result: CrCl 88.89 mL/min
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Age
- Weight
- Serum creatinine
- Sex
What this is
Sophie Well returns the value in mL/min, the unit most drug labels still print.
When to use it
Use Cockcroft-Gault when a drug label or renal-dose adjustment table specifies CrCl rather than eGFR - this is still the FDA-default unit for most package inserts (vancomycin, DOACs, gabapentin, many antibiotics). For staging chronic kidney disease, use the race-free CKD-EPI 2021 eGFR instead; Cockcroft-Gault systematically over-estimates GFR in heavy patients and under-estimates in cachectic patients.
How this is calculated
Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31-41. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.
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