eGFR Suite (CKD-EPI 2021 / MDRD / CG)
Renal-function panel: CKD-EPI 2021 eGFR, MDRD eGFR, and Cockcroft-Gault creatinine clearance side by side.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Serum creatinine
- 1.0 mg/dL
- Age
- 60 years
- Weight
- 70 kg
- Sex
- Male
Result: CKD-EPI 2021 ~89; MDRD ~77; Cockcroft-Gault ~78 mL/min
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Serum creatinine
- Age
- Weight (Cockcroft-Gault only)
- Sex
What this is
Estimate glomerular filtration rate using three published equations side by side: CKD-EPI 2021 (the race-free equation now endorsed by NKF and ASN), MDRD (the legacy four-variable equation many older studies report), and Cockcroft-Gault (which estimates creatinine clearance rather than GFR and is still the FDA reference for many drug-dosing labels). Sophie Well takes serum creatinine, age, sex, and weight, then returns all three estimates so a clinician can see how the choice of equation changes the number for a given patient.
When to use it
Use this when reviewing a patient with chronic kidney disease and a recent creatinine, when a drug label specifies a CrCl threshold (vancomycin, DOACs, gabapentin, sotalol) and the EHR is reporting eGFR instead, or when staging CKD against the KDIGO categories. Note: the CKD-EPI 2021 equation no longer uses a race coefficient - that was the explicit point of the 2021 update - so any prior NKF/ASN-aligned chart eGFR computed before the 2021 switch may not match what Sophie Well returns.
How this is calculated
Inker LA et al. NEJM 2021 (CKD-EPI race-free); Levey AS et al. Ann Intern Med 1999 (MDRD); Cockcroft-Gault Nephron 1976. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.
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