MDACC CLL Prognostic Index
MD Anderson CLL prognostic index (Wierda 2007): age, beta-2-microglobulin, absolute lymphocyte count, male sex, advanced Rai stage, and number of involved nodal groups give a score banding survival.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 70 years
- Beta-2-microglobulin
- > 2x ULN (2)
- Absolute lymphocyte count
- 60 ×10⁹/L
- Male sex
- Yes
- Advanced Rai stage
- No
- ≥ 3 involved nodal groups
- No
Result: MDACC CLL index 7 — intermediate risk (4-7).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- <= 3
- Low risk.
- 4-7
- Intermediate risk.
- >= 8
- High risk. Age, B2M band, ALC, male, Rai III-IV, >= 3 nodal groups. A prognostic index, not a treatment order.
What you enter
- Age
- Beta-2-microglobulin (× ULN band)
- Absolute lymphocyte count
- Male sex
- Advanced Rai stage (III–IV)
- ≥ 3 involved nodal groups
How this is calculated
Wierda WG, O’Brien S, Wang X, et al. Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia. Blood. 2007;109(11):4679-4685. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.