FLIPI-2 (Follicular Lymphoma Prognostic Index 2)
Follicular-Lymphoma International Prognostic Index 2 (FLIPI-2): five equally-weighted factors stratifying into low/intermediate/high risk.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age > 60
- Yes
- Elevated β₂-microglobulin
- Yes
- Hemoglobin < 12 g/dL
- Yes
Result: FLIPI-2 3 factors — high risk (~19% 5-year PFS).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Risk
- Low 0, intermediate 1–2, high 3–5. Uses β₂-microglobulin where the original FLIPI uses LDH and stage.
What you enter
- Age > 60
- Elevated β₂-microglobulin
- Longest node > 6 cm
- Bone-marrow involvement
- Hemoglobin < 12 g/dL
How this is calculated
- Factors
- Age > 60, elevated β₂-microglobulin, longest node > 6 cm, marrow involvement, Hb < 12 (1 point each).
Federico M, Bellei M, Marcheselli L, et al. Follicular Lymphoma International Prognostic Index 2: a new prognostic index for follicular lymphoma. J Clin Oncol. 2009;27(27):4555-4562. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.