Kinetic eGFR When Creatinine Is Changing (Chen)
Kinetic eGFR for a creatinine that is still changing, from a baseline and two consecutive creatinines.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Baseline (steady-state) creatinine
- 1 mg/dL
- Clearance or eGFR at that baseline
- 100 mL/min
- First creatinine
- 1 mg/dL
- Second creatinine
- 2 mg/dL
- Hours between the two
- 24 hours
- Weight
- 70 kg
Result: Kinetic eGFR 47.22 mL/min (30 to 59); the baseline estimate was 100 (60 or more).
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Baseline (steady-state) creatinine
- Clearance or eGFR at that baseline
- First creatinine
- Second creatinine
- Hours between the two
- Weight (or enter the maximum rise per day)
- Maximum creatinine rise per day
How this is calculated
Citation
Chen S. Retooling the creatinine clearance equation to estimate kinetic GFR when the plasma creatinine is changing acutely. J Am Soc Nephrol. 2013;24(6):877-888; equation as reproduced in Kwong YD, et al. PLoS One. 2019;14:e0225601, Fig 1. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.