High-Dose Insulin Euglycemia (HIET) Dosing
High-dose insulin euglycemia therapy (HIET) dosing for calcium-channel-blocker / beta-blocker poisoning: bolus, starting infusion, and titration ceiling from weight.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Body weight
- 80
Result: HIET: bolus 80 units (1 unit/kg), starting infusion 80 units/hr (1 unit/kg/hr), titration ceiling 800 units/hr (10 unit/kg/hr); pair with a dextrose infusion to maintain euglycemia.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Bolus + infusion
- regular-insulin bolus 1 unit/kg, infusion start 1 unit/kg/hr titratable to a 10 unit/kg/hr ceiling.
- Euglycemia coupling
- pair with a dextrose infusion and frequent glucose/potassium monitoring. Confirm against your institutional protocol and a second check.
What you enter
- Body weight (kg)
- Bolus dose override (units/kg)
- Starting infusion override (units/kg/hr)
How this is calculated
Engebretsen KM, Kaczmarek KM, Morgan J, Holger JS. High-dose insulin therapy in beta-blocker and calcium channel-blocker poisoning. Clin Toxicol (Phila). 2011;49(4):277-283. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.