TCA Toxicity: QRS Risk & Bicarbonate Target
TCA Toxicity: QRS Risk & Bicarbonate Target - a deterministic tool in Sophie Well's Medication & Infusion group.
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What this is
TCA Toxicity: QRS Risk & Bicarbonate Target is one of 230 deterministic tools in Sophie Well's Medication & Infusion group. TCA Toxicity: QRS Risk & Bicarbonate Target - a deterministic tool in Sophie Well's Medication & Infusion group.
When to use it
Use this tool when you need a quick, citable reference. Every calculation runs entirely in your browser - no inputs leave your device, no account is required, no AI is involved. The site enforces a strict Content Security Policy and ships no analytics or third-party CDN.
References
Boehnert MT, Lovejoy FH Jr. Value of the QRS duration versus the serum drug level in predicting seizures and ventricular arrhythmias after an acute overdose of tricyclic antidepressants. N Engl J Med. 1985;313(8):474-479. Read the source ↗
Worked example: QRS 120 ms (>= 100 ms): seizure risk -- give sodium bicarbonate 1-2 mEq/kg = 70-140 mEq, target serum pH 7.45-7.55.
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