HCT-CI (Transplant Comorbidity Index, Sorror)
Sorror HCT-CI hematopoietic-cell-transplantation comorbidity index (Sorror 2005): weighted organ comorbidities sum to a score banding non-relapse mortality (0 low, 1–2 intermediate, ≥ 3 high).
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Prior solid tumor
- Yes
Result: HCT-CI 3 — high risk (≥ 3).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Groups
- Low 0, intermediate 1–2, high ≥ 3. The pre-transplant non-relapse-mortality risk estimate, not a go/no-go order.
What you enter
- Arrhythmia (+1)
- Cardiac — CAD / CHF / MI / EF ≤ 50% (+1)
- Inflammatory bowel disease (+1)
- Diabetes on treatment (+1)
- Cerebrovascular disease (+1)
- Psychiatric disturbance (+1)
- Obesity (BMI > 35) (+1)
- Infection — antibiotics past day 0 (+1)
The other 7 fields
- Rheumatologic disease (+2)
- Peptic ulcer needing treatment (+2)
- Moderate renal — Cr > 2 mg/dL / dialysis / transplant (+2)
- Prior solid tumor (+3)
- Heart-valve disease (+3)
- Hepatic disease
- Pulmonary disease
How this is calculated
- Weights
- +1 arrhythmia, cardiac, IBD, diabetes, CVA, psychiatric, obesity, infection, mild hepatic; +2 rheumatologic, peptic ulcer, moderate renal/pulmonary; +3 solid tumor, heart valve, severe lung/hepatic.
Sorror ML, Maris MB, Storb R, et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood. 2005;106(8):2912-2919. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.