Acute GVHD Grade (Modified Glucksberg)
Acute graft-versus-host disease (GVHD) overall grade, modified Glucksberg (Przepiorka 1995).
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Liver stage
- 2 — bilirubin 3-6 mg/dL
Result: Acute GVHD grade III (modified Glucksberg): liver stage 2 gives a severe grade.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- I
- Skin stage 1-2 only, with no liver or GI involvement.
- II
- Skin stage 3, or liver stage 1, or GI stage 1.
- III
- Liver stage 2-3 or GI stage 2-3. Severe.
- IV
- Any organ at stage 4 (skin bullae, bilirubin >15, or GI >2000 mL/day or ileus). Severe.
What you enter
- Skin stage (by BSA rash)
- Liver stage (by bilirubin)
- Lower GI stage (by diarrhea volume)
How this is calculated
Przepiorka D, Weisdorf D, Martin P, et al. 1994 Consensus Conference on Acute GVHD Grading. Bone Marrow Transplant. 1995;15(6):825-828. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.