Chronic GVHD global severity (NIH 2014)
Reads the NIH 2014 consensus global severity of chronic graft-versus-host disease.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Skin score
- 1 - mild, no significant impairment
- Mouth score
- 1 - mild, no significant impairment
- Eye score
- 0 - not involved
- Gastrointestinal tract score
- 0 - not involved
- Liver score
- 0 - not involved
- Lung score
- 1 - mild, no significant impairment
- Joints and fascia score
- 0 - not involved
- Genital tract score
- 0 - not involved
Result: moderate, on the lung score alone
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Mild
- One or two organs scored 1, with the lung at 0.
- Moderate
- Any organ scored 2, or three or more organs scored 1, or a lung score of 1.
- Severe
- Any organ scored 3, or a lung score of 2 or 3.
- The lung
- Scores on its own. A lung score of 1 is at least moderate and 2 or 3 is severe, whatever every other organ shows.
- Not assessed
- An organ never looked at is not an organ known to be uninvolved, and a blank is not read as a zero.
- Before scoring
- The diagnosis is assumed already made: at least one diagnostic manifestation, or a distinctive one with confirmatory testing.
What you enter
- Skin score
- Mouth score
- Eye score
- Gastrointestinal tract score
- Liver score
- Lung score (this organ can set the grade on its own)
- Joints and fascia score
- Genital tract score
How this is calculated
Jagasia MH, Greinix HT, Arora M, et al. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group Report. Biol Blood Marrow Transplant. 2015;21(3):389-401. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.