Digoxin maintenance dose + level interpretation

Digoxin maintenance guidance and level interpretation (ACC/AHA/HFSA 2022): renal/age-adjusted dose guidance, indication-specific target range, and a <6 h post-dose timing warning.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Creatinine clearance
60 mL/min
Indication
Heart failure (target 0.5-0.9 ng/mL)
Measured level
0.7 ng/mL
Hours post-dose
8 h

Result: Maintenance 0.125-0.25 mg PO daily; level 0.7 ng/mL within the 0.5-0.9 ng/mL HF target.

The tool opens with these values already filled in. Replace them with your own.

What you enter

  • Creatinine clearance
  • Age (optional)
  • Indication
  • Measured level (optional; for the level interpretation)
  • Hours post-dose (optional; for the draw-timing warning)
How this is calculated

ACC/AHA/HFSA 2022 Heart Failure Guideline (Heidenreich PA, et al. Circulation. 2022;145(18):e895-e1032); HF digoxin level target 0.5-0.9 ng/mL. Maintenance guidance is renal/age-categorical (dosing varies too widely for a fixed estimate). Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.