Siponimod (Mayzent) Maintenance Dose by CYP2C9 Genotype (FDA Label)
The Mayzent label dosage for a CYP2C9 genotype.
Open the tool → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- CYP2C9 genotype on the report
- *1/*3
Result: Label dosage: a 4-day titration, then 1 mg once daily starting on Day 5.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- CYP2C9 genotype on the report
How this is calculated
Citation
FDA label on DailyMed, Mayzent (siponimod), Novartis: sections 2.2 and 2.3 (dosage by CYP2C9 genotype, Tables 1 and 2), section 4 (*3/*3 contraindicated) and section 8.6 (variants other than *2 and *3 not evaluated). Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.