Eliglustat (Cerdelga) Dose by CYP2D6 Status (FDA Label)
The Cerdelga label dosage for a CYP2D6 status.
Open the tool → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- CYP2D6 metabolizer status
- Extensive (normal) metabolizer
- Hepatic impairment
- No hepatic impairment
- Renal function
- No renal impairment
- Concomitant CYP2D6 inhibitor
- Strong
- Concomitant CYP3A inhibitor
- None
Result: Label dosage: 84 mg once daily.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- CYP2D6 metabolizer status
- Hepatic impairment
- Renal function
- Concomitant CYP2D6 inhibitor
- Concomitant CYP3A inhibitor
How this is calculated
Citation
FDA label on DailyMed, Cerdelga (eliglustat), Genzyme: section 1 (limitations of use), 2.2 and 2.3 (Tables 1 and 2), 4 (contraindications by CYP2D6 status), 7.1 (Table 5) and 8.6 and 8.7 (renal and hepatic impairment). Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.