Digoxin Loading and Maintenance (Label Method)
Digoxin loading schedule and maintenance dose by the method on the FDA tablets label.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age group
- Adult or child over 10 years
- Lean body weight
- 70
- Weight unit
- kg
- Loading dose chosen
- 10 mcg/kg
- Corrected creatinine clearance
- 55 mL/min
Result: Loading 700 mcg in all (350 mcg, then 175 mcg twice), within the label range; maintenance 250 mcg daily by the table, 175 mcg by the formula.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Age group: adult or child over 10 years (over-10), or 5 to 10 years (5-10)
- Lean body weight
- Weight unit
- Loading dose chosen
- Corrected creatinine clearance (for maintenance, over 10 years)
- Or, for an adult: serum creatinine (the label estimates the clearance)
- Age, with a serum creatinine
- Sex, with a serum creatinine
- Tablet dose to convert to intravenous
How this is calculated
Citation
FDA label on DailyMed, Digoxin tablets, sections 2.2 to 2.6: loading 10 to 15 mcg/kg (20 to 45 at ages 5 to 10), half then two quarters; maintenance = loading dose × (14 + creatinine clearance ÷ 5) ÷ 100; and the once-daily maintenance table by lean weight and clearance. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.