Van Nuys Prognostic Index (USC/VNPI, DCIS)
USC/Van Nuys Prognostic Index (VNPI) for DCIS, 4-factor 2003 update: tumor size (mm), margin width (mm), pathologic classification (1-3), and age (years), each scored 1-3 and summed to 4-12.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Tumor size (mm); binned <=15 = 1, 16-40 = 2, >=41 = 3
- 20
- Margin width (mm); binned >=10 = 1, 1 to <10 = 2, <1 = 3
- 5
- Pathologic classification
- 3 — high grade (nuclear grade 3)
- Age (years); binned >60 = 1, 40-60 = 2, <40 = 3
- 45
Result: USC/VNPI 9 of 12 — intermediate risk.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Risk
- total 4-6 = low, 7-9 = intermediate, 10-12 = high. Decision support for the treatment discussion, not a treatment order.
What you enter
- Tumor size (mm); binned <=15 = 1, 16-40 = 2, >=41 = 3
- Margin width (mm); binned >=10 = 1, 1 to <10 = 2, <1 = 3
- Pathologic classification: 1 = non-high grade no necrosis, 2 = non-high grade with necrosis, 3 = high grade
- Age (years); binned >60 = 1, 40-60 = 2, <40 = 3
How this is calculated
- Factors
- four items each 1-3: size (<=15 / 16-40 / >=41 mm), margin (>=10 / 1-9 / <1 mm), classification (non-high no necrosis / non-high + necrosis / high grade), age (>60 / 40-60 / <40 y); total 4-12.
Silverstein MJ. The University of Southern California/Van Nuys prognostic index for ductal carcinoma in situ of the breast. Am J Surg. 2003;186(4):337-343. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.