SLICC 2012 SLE Classification Criteria

SLICC 2012 SLE classification: ≥ 4 of 17 criteria with ≥ 1 clinical and ≥ 1 immunologic, OR biopsy-proven lupus nephritis with ANA or anti-dsDNA.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Acute cutaneous lupus
Yes
Synovitis
Yes
Renal involvement
Yes
ANA
Yes

Result: Meets SLICC 2012 criteria for SLE.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Count pathway
≥ 4 of the 17 criteria (11 clinical + 6 immunologic) with at least 1 clinical AND at least 1 immunologic.
Biopsy pathway
Biopsy-proven lupus nephritis with ANA or anti-dsDNA classifies regardless of total count.

What you enter

  • Acute cutaneous lupus
  • Chronic cutaneous lupus
  • Oral / nasal ulcers
  • Nonscarring alopecia
  • Synovitis
  • Serositis
  • Renal involvement
  • Neurologic involvement
The other 10 fields
  • Hemolytic anemia
  • Leukopenia
  • Thrombocytopenia
  • ANA (immunologic)
  • Anti-dsDNA (immunologic)
  • Anti-Sm (immunologic)
  • Antiphospholipid antibody (immunologic)
  • Low complement (immunologic)
  • Direct Coombs (immunologic)
  • Biopsy-proven lupus nephritis (shortcut pathway)
How this is calculated

Petri M, Orbai AM, Alarcón GS, et al. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum. 2012;64(8):2677-2686. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.