PSA velocity
PSA velocity (Carter 1992): the annualized rate of PSA rise between two measurements (ng/mL/yr); above 0.75 ng/mL/yr raises suspicion for cancer.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Earlier PSA
- 3 ng/mL
- Later PSA
- 4.5 ng/mL
- Interval
- 12 months
Result: PSA velocity +1.5 ng/mL/yr (over 12 months): above 0.75 ng/mL/yr, raising suspicion for cancer.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Reading
- above 0.75 ng/mL/yr raises suspicion for cancer; a lower threshold (~0.35-0.4) applies when baseline PSA is below 4.
What you enter
- Earlier PSA
- Later PSA
- Interval
How this is calculated
- Formula
- two-point rate = (later PSA - earlier PSA) / interval in years; the validated method averages consecutive yearly rates over >= 3 measurements spanning >= 18 months.
Carter HB, Pearson JD, Metter EJ, et al. Longitudinal evaluation of prostate-specific antigen levels in men with and without prostate disease. JAMA. 1992;267(16):2215-2220. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.