PSA density

PSA density (Benson 1992): serum PSA divided by prostate volume (ng/mL/cc); above 0.15 raises suspicion for clinically significant cancer.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Serum PSA
6 ng/mL
Prostate volume
30 cc

Result: PSA density 0.2 ng/mL/cc (PSA 6 / volume 30 cc): above 0.15, raising suspicion for clinically significant cancer.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Reading
above 0.15 ng/mL/cc raises suspicion for clinically significant cancer and helps refine biopsy decisions in the PSA gray zone.

What you enter

  • Serum PSA
  • Prostate volume
How this is calculated
Formula
PSA density = serum PSA (ng/mL) / prostate volume (cc).

Benson MC, Whang IS, Pantuck A, et al. Prostate specific antigen density: a means of distinguishing benign prostatic hypertrophy and prostate cancer. J Urol. 1992;147(3 Pt 2):815-816. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.