NCCN-IPI for DLBCL
NCCN-IPI for DLBCL (Zhou 2014): a 0–8 score from banded age, LDH ratio, advanced stage, ECOG ≥ 2, and major extranodal involvement.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 70
- LDH / upper-limit-of-normal ratio
- 2.5
- Ann Arbor stage III–IV
- Yes
- ECOG performance status ≥ 2
- No
- Major extranodal site
- No
Result: NCCN-IPI 4 of 8 -- High-intermediate risk; 5-year overall survival ~64%. Counted: age > 60-75 (2), LDH ratio > 1-3x (1), stage III-IV (1).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0-1
- Low; 5-year OS ~96%.
- 2-3
- Low-intermediate; 5-year OS ~82%.
- 4-5
- High-intermediate; 5-year OS ~64%.
- 6-8
- High; 5-year OS ~33%.
What you enter
- Age (years)
- LDH / upper-limit-of-normal ratio
- Ann Arbor stage III–IV
- ECOG performance status ≥ 2
- Major extranodal site (marrow/CNS/liver/GI/lung)
How this is calculated
Zhou Z, Sehn LH, Rademaker AW, et al. An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era. Blood. 2014;123(6):837-842. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.