Lok Index (cirrhosis probability)
Lok index for cirrhosis (Lok 2005, HALT-C): a logistic probability from platelets, the AST/ALT ratio, and INR.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Platelet count
- 120 10^9/L
- AST
- 60 U/L
- ALT
- 50 U/L
- INR
- 1.2
Result: Lok index 0.77: above 0.5 -- cirrhosis is likely.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Thresholds
- below 0.2 rules cirrhosis out; above 0.5 rules it in; between is indeterminate.
What you enter
- Platelet count
- AST
- ALT
- INR
How this is calculated
- Formula
- x = -5.56 - 0.0089 x platelets + 1.26 x (AST/ALT) + 5.27 x INR; probability = e^x / (1 + e^x).
Lok AS, Ghany MG, Goodman ZD, et al. Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests: results of the HALT-C cohort. Hepatology. 2005;42(2):282-292. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.