Goteborg University Cirrhosis Index (GUCI)
Goteborg University Cirrhosis Index (Islam S, et al. Scand J Gastroenterol 2005) = (AST / upper-limit-of-normal) x INR x 100 / platelet count (10^9/L); a value > 1.0 suggests cirrhosis.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- AST
- 60 U/L
- AST upper limit of normal
- 40 U/L
- INR
- 1.2
- Platelet count
- 150 10^9/L
Result: GUCI 1.2 — above the ~1.0 cirrhosis threshold.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- <= 1.0
- Below the cirrhosis threshold.
- > 1.0
- Suggests cirrhosis (AST/ULN x INR x 100 / platelets; sens ~80%, spec ~78%). A non-invasive index, not a diagnosis.
What you enter
- AST
- AST upper limit of normal
- INR
- Platelet count
How this is calculated
Islam S, Antonsson L, Westin J, Lagging M. Cirrhosis in hepatitis C virus-infected patients can be excluded using an index of standard biochemical serum markers. Scand J Gastroenterol. 2005;40(7):867-872. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.