Lung Immune Prognostic Index (LIPI)
Lung Immune Prognostic Index (Mezquita 2018): the derived neutrophil-to-lymphocyte ratio (from ANC and total WBC) plus elevated LDH give a 0–2 score banding prognosis on immunotherapy.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Absolute neutrophil count
- 7 ×10⁹/L
- Total WBC
- 9 ×10⁹/L
- LDH above the upper limit of normal
- Yes
Result: Lung Immune Prognostic Index 2 — poor prognostic group.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0
- Good prognostic group.
- 1
- Intermediate.
- 2
- Poor. dNLR = ANC/(WBC-ANC); one point each dNLR > 3 and LDH > ULN. Not a treatment order.
What you enter
- Absolute neutrophil count
- Total WBC
- LDH above the upper limit of normal
How this is calculated
Mezquita L, Auclin E, Ferrara R, et al. Association of the Lung Immune Prognostic Index with immune checkpoint inhibitor outcomes in patients with advanced non-small cell lung cancer. JAMA Oncol. 2018;4(3):351-357. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.