GRIm-Score (Gustave Roussy Immune Score)
GRIm-Score (Bigot 2017): serum albumin, neutrophil-to-lymphocyte ratio, and elevated LDH give a 0–3 score where a higher total marks worse survival on immunotherapy.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Serum albumin
- 3.0 g/dL
- Neutrophil-to-lymphocyte ratio
- 8
- LDH above the upper limit of normal
- Yes
Result: GRIm-Score 3 — high risk (2-3): worse survival on immunotherapy.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0-1
- Low risk.
- 2-3
- High risk: worse overall survival on immune-checkpoint therapy. One point each: LDH > ULN, albumin < 3.5, NLR > 6. Not a treatment order.
What you enter
- Serum albumin
- Neutrophil-to-lymphocyte ratio
- LDH above the upper limit of normal
How this is calculated
Bigot F, Castanon E, Baldini C, et al. Prospective validation of a prognostic score for patients in immunotherapy phase I trials: the Gustave Roussy Immune Score (GRIm-Score). Eur J Cancer. 2017;84:212-218. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.