IV / PN osmolarity + central-line flag
Estimated IV/PN solution osmolarity (ASPEN 2014): dextrose% x 50 + amino acid% x 100 + (Na + K mEq/L) x 2, against the FDA labels' central-vein threshold (900 mOsm/L or greater).
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Dextrose
- 5 %
- Amino acids
- 2.5 %
- Sodium additives
- 30 mEq/L
- Potassium additives
- 20 mEq/L
Result: Estimated osmolarity 600 mOsm/L — below 900 mOsm/L by this estimate; may be given through a central or peripheral vein.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Dextrose
- Amino acids
- Sodium additives
- Potassium additives
- By component (optional), one per line: labeled osmolarity in mOsm/L, volume in mL
How this is calculated
Citation
Estimate (dextrose%x50 + amino-acid%x100 + (Na+K mEq/L)x2): Boullata JI, et al. ASPEN Safe Practices. JPEN. 2014;38(3):334-377. Central vein at 900 mOsm/L or greater: FDA labels (Intralipid, SMOFlipid, Omegaven). Pediatric peripheral limit of 718 mOsm/L: TrophAmine 10% label. Read the sources: Boullata 2014 ↗, Intralipid 20% label ↗, Omegaven label ↗, TrophAmine label ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.