Weight-based heparin infusion nomogram
Raschke 1993 weight-based heparin nomogram: VTE 80 u/kg bolus + 18 u/kg/h or ACS 60 u/kg (max 4000) + 12 u/kg/h (max 1000), with aPTT-driven titration steps.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Weight
- 80 kg
- Indication
- VTE (80 u/kg bolus, 18 u/kg/h)
- Current aPTT
- 40 seconds
Result: Initial bolus 6400 units, rate 1440 units/h; aPTT 40 s -> rebolus 3200 units, increase 160 units/h.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Weight
- Indication
- Current aPTT (optional; for the adjustment step)
How this is calculated
Raschke RA, et al. Ann Intern Med. 1993;119(9):874-881 (weight-based heparin nomogram). VTE 80 u/kg bolus + 18 u/kg/h; ACS 60 u/kg bolus (max 4000) + 12 u/kg/h (max 1000). Titration bands are user-selectable to the institutional aPTT/anti-Xa nomogram. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.