Gold Coast Criteria (ALS diagnosis, 2020)
Applies the 2020 Gold Coast criteria for diagnosing ALS.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Progressive motor impairment
- Yes
- Other diseases excluded
- Yes
- Cervical UMN dysfunction
- Yes
- Cervical LMN dysfunction
- Yes
Result: Gold Coast criteria met
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Required 1
- Progressive motor impairment documented by history or repeated clinical assessment, preceded by normal motor function.
- Required 2
- Either upper- and lower-motor-neuron dysfunction in at least one body region WITH BOTH IN THAT SAME REGION, or lower-motor-neuron dysfunction in at least two regions.
- Required 3
- Investigations excluding other diseases.
- Regions
- Bulbar, cervical, thoracic, lumbosacral.
- The trap
- Upper-motor-neuron signs in one region and lower-motor-neuron signs in a DIFFERENT region satisfy neither limb. Counting UMN and LMN regions separately gets this wrong.
- No categories
- Gold Coast abolished definite, probable and possible ALS. Those belonged to revised El Escorial and Awaji, and were dropped for increasing uncertainty and costing sensitivity.
- Sensitivity
- A multicentre comparison: Gold Coast 92 percent, revised El Escorial 88.6 percent, Awaji 90.3 percent.
What you enter
- Progressive motor impairment
- Other diseases excluded
- Bulbar UMN dysfunction
- Bulbar LMN dysfunction
- Cervical UMN dysfunction
- Cervical LMN dysfunction
- Thoracic UMN dysfunction
- Thoracic LMN dysfunction
The other 2 fields
- Lumbosacral UMN dysfunction
- Lumbosacral LMN dysfunction
How this is calculated
Shefner JM, Al-Chalabi A, Baker MR, et al. A proposal for new diagnostic criteria for ALS. Clin Neurophysiol. 2020;131(8):1975-1978. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.