Anaphylaxis Diagnostic Criteria (2020 WAO)
Decides whether a reaction meets the diagnostic criteria for anaphylaxis (2020 World Allergy Organization).
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Skin or mucosal involvement
- Yes
- Respiratory compromise
- Yes
Result: Anaphylaxis criteria met by criterion 1 - anaphylaxis is highly likely. Epinephrine is first-line.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Criterion 1
- Acute skin or mucosal involvement PLUS at least one of respiratory compromise, reduced blood pressure or end-organ dysfunction, or severe gastrointestinal symptoms.
- Criterion 2
- Acute hypotension, bronchospasm or laryngeal involvement after a known or highly probable allergen - even with NO skin involvement.
- Alternatives
- Either alone is enough; they are not steps. The second exists precisely so a reaction with no rash still counts.
- Caution
- Anaphylaxis is a clinical diagnosis and epinephrine is first-line. Nothing here delays it, and not meeting either criterion does not exclude it.
What you enter
- Skin or mucosal involvement
- Respiratory compromise
- Reduced BP or end-organ signs
- Severe GI symptoms
- Known or probable allergen
- Hypotension
- Bronchospasm
- Laryngeal involvement
How this is calculated
Cardona V, Ansotegui IJ, Ebisawa M, et al. World Allergy Organization anaphylaxis guidance 2020. World Allergy Organ J. 2020;13(10):100472. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.