Gleason Grade Group (ISUP)
Gleason grade group (Epstein 2016; ISUP 2014): maps the primary + secondary Gleason patterns to the 1-5 grade group with its prognostic band.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Primary (most common) pattern
- Pattern 3
- Secondary pattern
- Pattern 4
Result: Gleason 3+4 = 7, Grade Group 2 of 5: favorable intermediate grade.
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Mapping
- GG1 = Gleason 6 or below; GG2 = 3+4 = 7; GG3 = 4+3 = 7; GG4 = Gleason 8; GG5 = Gleason 9-10.
- Reading
- the primary pattern governs the 3+4 (GG2) versus 4+3 (GG3) split; higher groups carry worse prognosis.
What you enter
- Primary (most common) pattern
- Secondary pattern
How this is calculated
Epstein JI, Egevad L, Amin MB, et al. The 2014 ISUP consensus conference on Gleason grading of prostatic carcinoma. Am J Surg Pathol. 2016;40(2):244-252. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.