Three-Bag, 12-Step Desensitization Arithmetic

Three-bag, 12-step drug desensitization arithmetic, following the published table.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Total target dose
600 mg
Volume of each bag
250 mL
Final rate, step 12
80 mL/h

Result: Three 250 mL bags at 0.024, 0.24 and 2.381 mg/mL; 12 steps over 339.38 minutes (5.66 hours) deliver 600 mg.

The tool opens with these values already filled in. Replace them with your own.

What you enter

  • Total target dose
  • Volume of each bag (250 in the published table)
  • Final rate, step 12 (80 in the published table)
How this is calculated

Citation

Tsao LR, Young FD, Otani IM, Castells MC. Hypersensitivity Reactions to Platinum Agents and Taxanes. Clin Rev Allergy Immunol 2022;62:432-448, Table 5 (CC BY 4.0), after Castells MC, et al. J Allergy Clin Immunol 2008;122:574-580. Read the sources: Tsao 2022 ↗, Castells 2008 ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.