Renal Limits for Eight CNS Drugs (FDA Label)
The renal limit the FDA label gives for eight CNS drugs.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Drug
- Levetiracetam (Keppra)
- Dialysis
- Not on dialysis
- Creatinine clearance
- 60 mL/min
- Levetiracetam
- 2 m²
Result: The Keppra label gives 500 to 1,000 mg every 12 hours.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Drug
- Dialysis: none, hd or pd
- Creatinine clearance (GFR for duloxetine)
- Levetiracetam: body surface area
- Daily dose to check against the row maximum (optional)
- Lacosamide maximum dosage, or topiramate usual adult dose (for those rows)
How this is calculated
Citation
FDA labels on DailyMed, renal dosing sections: Keppra (2.5, Table 1), Vimpat (2.4), Topamax (2.5, 2.6), memantine extended-release, tramadol tablets, duloxetine (2.7), Pristiq (2.2) and Chantix. Read the sources: Keppra ↗, Vimpat ↗, Topamax ↗, Memantine ER ↗, Tramadol ↗, Duloxetine ↗, Pristiq ↗, Chantix ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.