CLIF-C AD (Acute Decompensation, pre-ACLF)
CLIF-C AD score (Jalan 2015): a mortality model for hospitalized decompensated cirrhosis without acute-on-chronic liver failure from age, creatinine, INR, WBC, and sodium; ≥ 60 is the high-risk band.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 65 years
- Creatinine
- 2.0 mg/dL
- INR
- 1.6
- WBC
- 12 ×10⁹/L
- Sodium
- 128 mmol/L
Result: CLIF-C AD 70 — high-risk band (≥ 60, ≈ 50% survival).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Bands
- < 50 low, 50–59 intermediate, ≥ 60 high risk (≈ 93% / 80% / 50% survival). The companion to CLIF-C ACLF for the pre-ACLF decompensated patient; a prognostic estimate, not an order.
What you enter
- Age
- Creatinine
- INR
- WBC
- Sodium
How this is calculated
- Formula
- CLIF-C ADs = 10 × [0.03·age + 0.66·ln(creatinine mg/dL) + 1.71·ln(INR) + 0.88·ln(WBC ×10⁹/L) − 0.05·sodium + 8]. Five predictors — the EF-CLIF calculator includes INR.
Jalan R, Pavesi M, Saliba F, et al. The CLIF Consortium Acute Decompensation score (CLIF-C ADs) for prognosis of hospitalised cirrhotic patients without acute-on-chronic liver failure. J Hepatol. 2015;62(4):831-840. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.