Brock / PanCan Nodule Malignancy Risk
Brock University nodule model (McWilliams 2013): estimates malignancy probability of a screen-detected pulmonary nodule from size, type, and clinical factors.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 70
- Nodule diameter
- 20
- Number of nodules
- 1
- Nodule type
- Part-solid
- Female sex
- Yes
- Family history of lung cancer
- Yes
- Emphysema on CT
- Yes
- Upper-lobe location
- Yes
- Spiculation on CT
- Yes
Result: Brock malignancy probability 80.1% -- high pretest probability (> 65%).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- Pretest
- a pragmatic framing reads < 5% as low, 5-65% as intermediate, and > 65% as high probability of malignancy.
What you enter
- Age (years)
- Nodule diameter (mm)
- Number of nodules
- Nodule type
- Female sex
- Family history of lung cancer
- Emphysema on CT
- Upper-lobe location
- Spiculation on CT
How this is calculated
- Model
- a logistic estimate validated on screening cohorts -- age, sex, family history, emphysema, a power transform of size, nodule type, upper-lobe location, count, and spiculation (age and count centered).
McWilliams A, Tammemagi MC, Mayo JR, et al. Probability of cancer in pulmonary nodules detected on first screening CT. N Engl J Med. 2013;369(10):910-919. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.