Banff Grade (Acute T Cell-Mediated Rejection)

The Banff grade of acute T cell-mediated rejection in a kidney allograft biopsy, read from three lesion scores a pathologist has already assigned.

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

i - interstitial inflammation
2
t - tubulitis
2
v - intimal arteritis
0

Result: i2 t2 v0: Banff grade IA acute T cell-mediated rejection.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Borderline
Tubulitis with i0 or i1, or i2/i3 with t1 only. No intimal arteritis.
IA / IB
i2 or i3 with t2 (IA) or t3 (IB), and no intimal arteritis.
IIA / IIB
v1 mild to moderate intimal arteritis (IIA); v2 severe, over 25% of the lumen (IIB).
III
v3 transmural arteritis, or fibrinoid change with medial smooth-muscle necrosis.

What you enter

  • i - interstitial inflammation (non-scarred cortex)
  • t - tubulitis (mononuclear cells per tubular cross-section)
  • v - intimal arteritis
How this is calculated

Loupy A, Haas M, Roufosse C, et al. The Banff 2019 Kidney Meeting Report (I): Updates on and clarification of criteria for T cell- and antibody-mediated rejection. Am J Transplant. 2020;20(9):2318-2331. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.