Antiepileptic Formulation and Route Switch (FDA Labels)
The dose when an antiepileptic changes formulation or route, as its label states it.
Open the tool → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Drug and switch
- Depakote (delayed-release) to Depakote ER
- Current total daily dose
- 1250 mg
Result: The Depakote ER label's table gives 1,500 mg of Depakote ER once daily for a Depakote total daily dose of 1,250 to 1,375 mg.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Drug and switch
- Current total daily dose (mg; phenytoin to fosphenytoin in mg PE)
How this is calculated
Citation
FDA labels on DailyMed: Depakote ER 2.2 (Table 1, conversion from Depakote), valproate sodium injection, Keppra injection, Tegretol, Cerebyx 2.6 and Dilantin Infatabs 2.5 (switching between formulations). Read the sources: Depakote ER label ↗, Valproate injection label ↗, Keppra injection label ↗, Tegretol label ↗, Cerebyx label ↗, Dilantin Infatabs label ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.