Acetaminophen (Rumack-Matthew) nomogram
Rumack-Matthew nomogram (US treatment line 150 ug/mL at 4 h): treatment-line level at the entered time post single acute ingestion and whether the measured level is above it.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Hours since single acute ingestion
- 4 h
- Serum acetaminophen
- 160 ug/mL
Result: Treatment line 150 ug/mL at 4 h; 160 ug/mL is above the line -> NAC indicated. Refuses outside 4-24 h.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Hours since single acute ingestion (4-24 h)
- Serum acetaminophen
How this is calculated
Rumack BH, Matthew H. Pediatrics. 1975;55(6):871-876; U.S. treatment line 150 ug/mL at 4 h (Rumack-Matthew). Valid only for a single acute ingestion with a known time, level drawn >=4 h. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.