UCSF Criteria (HCC Liver Transplant)

UCSF criteria for HCC liver-transplant eligibility (Yao 2001).

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Number of tumor nodules
2
Largest tumor diameter
4.0 cm
Total (summed) tumor diameter
7.0 cm

Result: Within UCSF criteria for HCC transplant.

The tool opens with these values already filled in. Replace them with your own.

What the result means

Within
a single tumor <= 6.5 cm, or <= 3 nodules with the largest <= 4.5 cm and total <= 8 cm.
Vetoes
gross vascular invasion or extrahepatic spread makes a patient ineligible regardless of size.
vs Milan
the expanded version of Milan (single <= 5 cm or <= 3 nodules each <= 3 cm).

What you enter

  • Number of tumor nodules
  • Largest tumor diameter (cm; single-tumor limit 6.5, multi-tumor limit 4.5)
  • Total (summed) tumor diameter (cm; multi-tumor limit 8)
  • Gross (macro)vascular invasion present
  • Extrahepatic spread present
How this is calculated

Yao FY, Ferrell L, Bass NM, et al. Liver transplantation for hepatocellular carcinoma: expansion of the tumor size limits does not adversely impact survival. Hepatology. 2001;33(6):1394-1403. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.