Toronto HCC Risk Index (THRI)

Toronto HCC Risk Index (THRI; Sharma 2017) — a validated score for 10-year HCC risk in cirrhosis from age, sex, cirrhosis etiology, and platelet count (total 0-366).

Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.

Example

Age
65 years
Sex
Male
Cirrhosis etiology
HCV (+97)
Platelet count
100 10^9/L

Result: Toronto HCC Risk Index 347/366

The tool opens with these values already filled in. Replace them with your own.

What the result means

< 120
Low risk — ~3% 10-year cumulative HCC incidence.
120-240
Medium risk — ~10% 10-year cumulative HCC incidence.
> 240
High risk — ~32% 10-year cumulative HCC incidence.

What you enter

  • Age
  • Sex
  • Cirrhosis etiology
  • Platelet count
How this is calculated
Points
Age <45/45-60/>60 = 0/50/100; etiology autoimmune or HCV-SVR = 0, other = 36, steatohepatitis = 54, HCV or HBV = 97; male = 80; platelets >200/140-200/80-139/<80 = 0/20/70/89.

Sharma SA, Kowgier M, Cerocchi O, et al. Toronto HCC risk index: a validated scoring system to predict 10-year risk of HCC in patients with cirrhosis. J Hepatol. 2017;68(1):92-99. Age, sex, etiology, platelets; total 0-366. Read the source ↗

A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.

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Built by Clay Good. Source on GitHub.