Alteplase and Tenecteplase Dose by Weight and Indication (Labels)
Alteplase and tenecteplase dose by weight and indication, from the labels.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Drug and indication
- Alteplase: acute ischemic stroke
- Weight
- 80 kg
Result: Alteplase 72 mg: 7.2 mg bolus over 1 minute, then 64.8 mg over 60 minutes.
The tool opens with these values already filled in. Replace them with your own.
What you enter
- Drug and indication
- Weight (not needed for pulmonary embolism)
- Cathflo under 30 kg: internal lumen volume of the catheter
How this is calculated
Citation
FDA labels on DailyMed: Activase (stroke 0.9 mg/kg to 90 mg; myocardial infarction, accelerated and 3-hour; pulmonary embolism 100 mg), TNKase (weight bands for stroke and STEMI) and Cathflo Activase (2 mg, or 110% of the lumen volume under 30 kg). Read the sources: Activase label ↗, TNKase label ↗, Cathflo Activase label ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.