SITS-SICH (Symptomatic ICH After Alteplase)
SITS-SICH score (Mazya 2012): antiplatelet therapy, NIHSS, glucose, systolic BP, weight, age, onset time, and hypertension predict symptomatic intracranial hemorrhage after IV alteplase.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Antiplatelet therapy
- Aspirin + clopidogrel (2)
- Admission NIHSS
- 15
- Blood glucose
- 200 mg/dL
- Systolic BP
- 150 mmHg
- Weight
- 80 kg
- Age
- 75 years
- Onset-to-treatment > 180 min
- Yes
- History of hypertension
- Yes
Result: SITS-SICH score 10 — high symptomatic-ICH risk (>= 9, ~23%).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- 0-2
- Low symptomatic-ICH risk after IV alteplase.
- 3-8
- Low-moderate to intermediate risk (~5-9%).
- >= 9
- High risk (~23%). A risk score, not a thrombolysis order.
What you enter
- Antiplatelet therapy (none / aspirin / aspirin + clopidogrel)
- Admission NIHSS
- Blood glucose
- Systolic BP
- Weight
- Age
- Onset-to-treatment > 180 min
- History of hypertension
How this is calculated
Mazya M, Egido JA, Ford GA, et al. Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: SITS symptomatic intracerebral hemorrhage risk score. Stroke. 2012;43(6):1524-1531. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.